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A 44-year-old member asked:

what's the etiology of chronic leukemia?

2 doctor answers3 doctors weighed in
Dr. David Rizzieri
Hematology and Oncology 30 years experience
Usually sporadic: CML is associated with a known genetic abnormality (t(9;22) - otherwise known as the philadelphia chromosome). It is not known what in the environment 'causes' this. Chronic lymphocytic leukemia has different common genetic changes, the causes of which also are not known. Rarely though, cll seems to run in families. This has led to significant research into what genetic drivers may be found.
Dr. Peter Wiernik
Hematology and Oncology 56 years experience
Wish I knew.: There is some evidence that excessive exposure to chemicals such as benzene may lead to an increased incidence of chronic myeloid leukemia, and excessive exposure to radiation has also been implicated. Cllhas been linked to pesticide exposure in some-but not all-studies. In animals, diseases like cll are usually caused by a virus. In practice a doctor rarely finds the cause of a patients leukemia.

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Similar questions

A 40-year-old member asked:

What are the chances of beating chronic leukemia?

1 doctor answer4 doctors weighed in
Dr. Liawaty Ho
Hematology and Oncology 23 years experience
Chronic leukemia: 2 big groups of chronic leukemia are- chronic myeloid leukemia (CML) and chronic lymphocytic leukemia (cll). The chance of beating CML is very good as the response to daily tyrosine kinase inhibitor therapy is amazing and the remission rate is high. In cll, however, therapy usually wont be needed on diagnosis if there is no indication.Also, many times people die of something else and not due to cll.
A 37-year-old member asked:

What is the difference between acute and chronic leukemia?

3 doctor answers7 doctors weighed in
Dr. Liawaty Ho
Hematology and Oncology 23 years experience
Everything: Acute leukemia is presented with the presence of significant level of a very immature blood cells in the circulation and increase level in the bone marrow. It is a very agressive and life threatening. Without treatment people die within weeks and few months only. Chronic leukemia- is progressing slower than acute leukemia. Chronic leukemia can transform into acute leukemia sometimes.
A 38-year-old member asked:

What are the tests for chronic leukemia?

2 doctor answers9 doctors weighed in
Dr. Liawaty Ho
Hematology and Oncology 23 years experience
Blood work etc: You would need at least- blood work. Imaging scan for abdomen would be needed in certain chronic leukemia ( cml) to evaluate spleen or if there is other indication ( such as presence of abdominal pain etc); a bone marrow biopsy will be needed in certain case of chronic leukemia. Please discuss further in detail with your hematologist/ oncologist. Read more at www.Cancer.Net ; www.Lls.Org.
Dr. Gurmukh Singh
Pathology 49 years experience
The general order of lab tests is CBC and examination of peripheral smear,followed by bone marrow examination. Study of cell surface markers on cells in blood and bone marrow and DNA changes in the same are now routine.
Jun 12, 2012
A 48-year-old member asked:

What are the major presenting symptoms associated with chronic leukemia?

1 doctor answer5 doctors weighed in
Dr. Liawaty Ho
Hematology and Oncology 23 years experience
Varies: Majority cases are asymptomatic and the evaluation is started due to abnormal blood work. When the leukemia is more advanced - patient can become symptomatic-and can be presented with-anemia, low platelet level- bleeding, increase white blood counts, recurrent infections, fatigue/decrease energy level, fever/chils/night sweats, increase abdominal girth etc. Read more : www.Cancer.Net / www.Lls.Org.
Dr. Michael Thompson
Hematology and Oncology 20 years experience
Chronic leukemia may also be found on CBC only and asymptomatic.
Jun 12, 2012
A 41-year-old member asked:

What are the symptoms of chronic leukemia?

1 doctor answer3 doctors weighed in
Dr. Romeo Mandanas
Hematology and Oncology 38 years experience
50% are asymptomatic: About half of patients with chronic leukemia have no symptoms and are discovered on a routine CBC (complete blood count) usually obtained for some other reason. When symptoms do occur, they may include fatigue or tiredness, swollen glands or lymph nodes, low grade fever or sweats that are persistent. More advanced symptoms can include, bleeding, bruising, anemia, enlarging belly or an infection.

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Last updated Jun 10, 2014
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