A member asked:

How is radio-immunotherapy administered?

3 doctors weighed in across 2 answers
Dr. Devon Webster answered

Specializes in Medical Oncology

In steps: Radio-immunotherapy (rit) is given in three steps, all through an iv. Step 1: an antibody to b cells alone to clear out some normal b cells. Step 2: an antibody to b cells with a small amount of radiation attached, followed by imaging. Step 3: a "hot" antibody to b cells with a larger dose of radiation attached. This acts like a smart bomb to kill cancerous b cells (lymphoma cells).

Answered 4/28/2012

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Radioimmunotherapy: Radioimmunotherapy (rit) uses an antibody labeled with a radionuclide to deliver cytotoxic radiation to a target cell. In cancer therapy, an antibody with specificity for a tumor-associated antigen is used to deliver a lethal dose of radiation to the tumor cells. The ability for the antibody to specifically bind to a tumor-associated antigen increases the dose delivered to the tumor cells.

Answered 3/21/2013

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