A 37-year-old member asked:

What is nephrogenic systemic fibrosis and what will a skin biopsy tell you?

1 doctor answer2 doctors weighed in
Dr. Simon Kimm
Urology 18 years experience
Affects skin, joints: Nephrogenic systemic fibrosis (nsf) is a serious condition where fibrosis of skin leads to scar-like nodules & plaques. Joints can be affected, leading to contractures & pain. Serious cases can lead to fibrosis of organs. The cause is unknown, but is related to kidney failure & exposure to gadolinium, used in mri. A skin biopsy is diagnostic, showing thickened collagen bundles & sclerotic bodies.
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Last updated Dec 28, 2016


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