A 36-year-old member asked:
Is tetralogy of fallot a hereditary problem?
1 doctor answer • 3 doctors weighed in
Maternal-Fetal Medicine 26 years experience
5.7k viewsReviewed >2 years ago
A 45-year-old member asked:
Is getting a tetralogy of fallot hereditary?
3 doctor answers • 9 doctors weighed in
Pediatrics 46 years experience
Complex gene impact: Heart defects develop from multiple genetic and non gene factors.They are not inherited directly like eye color or blood type. The general risk ~.5% will increase for any family factor. Mom, dad or another sibling with any heart defect increases the general risk/pregnancy. Exposures to certain meds, alcohol, inherited syndromes count. A second defect if it occurs, may be more or less complex.
6.2k viewsReviewed >2 years ago
A 48-year-old member asked:
Is tetralogy of fallot hereditary?
2 doctor answers • 5 doctors weighed in
Pediatric Cardiology 38 years experience
In some families: In some families, there are genetic factors that affect the development of various conotruncal heart defects, which includes tetralogy of fallot. One gene defect that can result in tof is 22q deletion. There is variability in both penetrance (does the disease show up) and expression (the exact way a disease occurs.).
4.6k viewsReviewed >2 years ago
Last updated Nov 18, 2015
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