U.S. doctors online nowAsk doctors free
A 36-year-old member asked:

Is tetralogy of fallot a hereditary problem?

1 doctor answer3 doctors weighed in
Dr. Nikolaos Zacharias
Maternal-Fetal Medicine 26 years experience
Not typically.: Most cases are isolated and sporadic. It accounts for 5-10% of all congenital heart defects. 15% of tof cases are part of known genetic syndromes (down, digeorge, alagille, phenylketonuria) or associations (charge/vacterl) and some are linked to poorly controlled preconceptional maternal diabetes mellitus. Recurrence risk: 2.5% with one prior affected child, 8% with two. Folic acid may prevent it!

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

Ask doctors free
Educational text
Free
Talk to a doctor
24/7 visits - just $39!
50% off with $15/month membership

Similar questions

A 45-year-old member asked:

Is getting a tetralogy of fallot hereditary?

3 doctor answers9 doctors weighed in
Dr. James Ferguson
Pediatrics 46 years experience
Complex gene impact: Heart defects develop from multiple genetic and non gene factors.They are not inherited directly like eye color or blood type. The general risk ~.5% will increase for any family factor. Mom, dad or another sibling with any heart defect increases the general risk/pregnancy. Exposures to certain meds, alcohol, inherited syndromes count. A second defect if it occurs, may be more or less complex.
A 48-year-old member asked:

Is tetralogy of fallot hereditary?

2 doctor answers5 doctors weighed in
Dr. Steven Neish
Pediatric Cardiology 38 years experience
In some families: In some families, there are genetic factors that affect the development of various conotruncal heart defects, which includes tetralogy of fallot. One gene defect that can result in tof is 22q deletion. There is variability in both penetrance (does the disease show up) and expression (the exact way a disease occurs.).

Related questions

A 31-year-old member asked:
1 doctor answer1 doctor weighed in
A 34-year-old member asked:
1 doctor answer1 doctor weighed in
A 32-year-old member asked:
2 doctor answers8 doctors weighed in
A 31-year-old member asked:
2 doctor answers7 doctors weighed in
A 44-year-old member asked:
1 doctor answer1 doctor weighed in

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

Ask doctors free
Educational text
Free
Talk to a doctor
24/7 visits - just $39!
50% off with $15/month membership
Last updated Nov 18, 2015

People also asked

Connect with a U.S. board-certified doctor by text or video anytime, anywhere.
24/7 visits - just $39!
50% off with $15/month membership

Disclaimer:

Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.