Infection in esophagus?

Possible: If you are asking if a person can get an infection in the esophagus, the answer is yes. Infection can occur in any part of the body. If you are asking about esophagitis, it does not have to be an actual infection caused by a bacteria, virus, fungus, or parasite. It can mean irritation of the esophageal mucosa from recurrent exposure to refluxed stomach acid, mostly affecting the lower esophagus.