A member asked:

Why does dcis become invasive?

4 doctors weighed in across 2 answers
Dr. Devon Webster answered

Specializes in Medical Oncology

Unknown: If we knew the answer to this question, women with dcis would not all need surgery! about 50% of dcis (ductal carcinoma in situ), if left untreated, will go on to become invasive cancer. Certain genes in the dcis cells get "turned on", making them invasive, but we don't know what makes this switch happen.

Answered 4/1/2014

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Dr. Scott Grover answered

Specializes in Surgery

Progression: Dcis is ductal cancer (breast) in situ, which means the cells are showing cancerous changes, but it is still contained within the cells. One way to think of it is early ductal cancer. If you do not undergo removal of the dcis is will pregress to become invasive cancer - spreading to the surrounding cells and tissues.

Answered 3/15/2012

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