Depends.: The onset of action is ~1 hour; the duration of action is ~24 hours. The time to eliminate 1/2 of the dose is 5 hours (half-life elimination). Source: wang z, lee b, pearce d, et al, "meclizine metabolism and pharmacokinetics: formulation on its absorption, " j clin pharmacol, 2011a, [epub ahead of print] [pubmed 21903894].
Answered 3/9/2020
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