A member asked:

How long does it take for zoloft (sertraline) generic to start working?

A doctor has provided 1 answer

Up to six weeks: First of all, there should be no real difference between generic sertraline and brand name zoloft. Also, it depends on what it being prescribed for and the dose you are taking. Sertraline is 50% better absorbed with food and i always tell my patients to take it every morning after breakfast. For major depression, 75% will respond in the first four weeks whereas 25% respond in 4-6 weeks.

Answered 4/12/2018

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