What do they do if nephrotic syndrome is not responding to prednisolone?

Nephrotic syndrome: Standard treatment appraoches to nephrotic syndrome in which your kidney is leaking out a lot of protein in your urine and leads to accumulation of excess body fluid [edema] is a steroid medication like prednisone. If that doesn't work, the next step is usually cytotoxic medications lik, e the medications that are used to treat cancer. A specialist will decide which is best for you.

See below: There is no uniform approach for the individuals with steroid-resistant nephrotic syndrome. Clinical trials utilizing cyclosporin, tacrolimus, or Mycophenolate Mofetil (mmf) with corticosteroid show variable success rate of inducing remission. Your nephrologist can provide you more details.