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A 43-year-old member asked:

Is there a difference between a codeine and morphine addiction?

2 doctor answers5 doctors weighed in
Dr. David Teicheira
Pain Management 36 years experience
Not a bit: Codeine has almost no analgesic activity in most people. After it is absorbed by the gut, the Codeine dissolved in blood passes through the liver wherre an enzyme converts it to morphine! some people (usually asian) lack this enzyme and get no effect from Codeine (except constipation). Morphine is available in larger dose pills, so, its easier to get dependant on higher doses.
Dr. Stuart Wasser
Addiction Medicine 35 years experience
A little: Codeine tolerance rarely gets as high as other opioids. Otherwise, no difference.

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A 48-year-old member asked:

What is the difference in potency between codeine and morphine?

2 doctor answers2 doctors weighed in
Dr. James Marx
Pain Management 48 years experience
Alot: Codeine to be effective needs to be converted to Morphine in your body. Some lack the ability to do that efficiently and consequently have poor analgesia and more side effects from Codeine. Generally, codeine is about 1/10 as effective as Morphine but for some even less effective.

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Last updated Jun 12, 2015
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