It can be really bad: It's thought to be immune mediated. It usually occurs within 6 hours of receiving a blood product (red cells, platelets, cryoprecipitate, or plasma) and has a mortality rate approaching 10% in some studies. It causes significant pulmonary edema usually requiring intubation. It usually resolves in 2-4 days with just supportive care alone.
Answered 3/20/2014
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