A member asked:

How can you treat progressive supranuclear palsy?

12 doctors weighed in across 3 answers
Dr. Felix Brizuela answered

Specializes in Neurology

Not good: Not very much except for supportive care. Doesn't respond well to drugs used for other types of parkinson's.

Answered 9/30/2020

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Good Rx Available!!!: Dopamine meds for physical parkinsonism: Azilect (mao-b selective inhibitor) & sinemet +/- Comtan (stalevo (carbidopa and levodopa and entacapone) is both together). Tailor rx & watch for side effects. Avoid Dopamine agonists (requip xl/mirapex er/neupro)--too side effect prone for psp patients. For dementia: namenda, paired with Exelon patch or aricept. For psychosis: seroquel or clozaril. Remember, response is variable, but worthwhile.

Answered 5/7/2016

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The right doctor: I believe it is important to be seen by a movement disorders neurologist for this neurodegenerative disease. This is a very difficult disease to treat. A patient may need very high doses of levodopa. Oftentimes issues such as feeding tubes are at the fore. A specialist will have more experience dealing with this rare disease and may have other options (i.e. Clinical trials) available.

Answered 5/18/2016

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