A member asked:

Pristiq (desvenlafaxine) vs effexor --are they different?

4 doctors weighed in across 2 answers
Dr. Pamela Pappas answered

Specializes in Psychiatry

Yes: Pristiq (desvenlafaxine) is the main metabolite of Effexor (venlafaxine). Pristiq may reduce the risk of drug interactions, because it isn't processed by the cyp2d6 liver enzyme system. Pristiq may have been created as a patent-extender when effexor's patent ran out. Some also feel that antidepressant effect can be achieved with lower dose of Pristiq than Effexor -- but clinical results vary.

Answered 9/16/2019

5.7k views

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Dr. Alan Ali answered

Specializes in Psychiatry

Pristiq (desvenlafaxine): Similar to Effexor-XR, being an isomer of Venlafaxine.

Answered 5/26/2015

2.8k views

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