A 45-year-old female asked:
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how does esophyx compare to nissen fundoplication in terms of efficacy and safety? i have bad gerd and laryngitis. which should i do?

2 doctor answers
Dr. Nicholas Karyotakis
29 years experience Gastroenterology
Both have pros&cons: Bad gerd with laryngitis that is poorly managed with meds makes you a candidate for either procedure. Esophyx is endoscopic without scars but is newer, less studied& not indicated for big hiatal hernia. Laparoscopic nissen fundoplication is the gold standard but it is a surgery/more expensive and makes it difficult to heave or burp. They are both operator dependent & patient selection is key.
Answered on Jun 6, 2017
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Dr. Jarrod Kaufman
28 years experience General Surgery
In certain instances this can also be addressed as a hybrid- combined laparoscopic and endoscopic procedure i.e fix the hiatal hernia lap and do the esophyx endoscopically.
Jun 6, 2017
Dr. Dan Lister
27 years experience General Surgery
Both are good. : Both are good. The nissen is 90-95% successful but has a relatively high side effect profile (up to 60% in some studies) for bloating and trouble swallowing. The esophyx is 80-85% successful but only has about a 2% bloat and dysphagia rate. A hybrid tif can be done to fix the hiatal hernia laparoscopically then do the transoral wrap with the esophyx device. Talk to a surgeon who does both.
Answered on Jun 6, 2017
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