A member asked:

What is pgd ? how does it help improve chances in an embryo transfer ?

7 doctors weighed in across 3 answers
Dr. Nikolaos Zacharias answered

Specializes in Maternal-Fetal Medicine

Preimplantation test: In ivf (in vitro fertilization) a new technique can now check the dna of each embryo for anomalies and only transfer cytogenetically healthy embryos, thus decreasing your chances for miscarriage and chromosomally abnormal offspring. It does little to improve your transfer success rate.

Answered 12/20/2015

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Respectfully disagree: In our experience, by doing pgs, or checking each embryo to make sure it is chromosomal normal not only improves pregnancy rates but decreases the risk of a miscarriage. Although some clinics disagree with this, our data definitely supports the increase pregnancy rates and decrease miscarriage rates with chromosome testing. Also, emotionally, you know that you transferred normal embryos; and if abnormal, at least you did not do an et and were hopeful and spend the money on a transfer.

Answered 1/28/2017

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PGS/PGD: Pgd is the diagnosis of a specific disorder (sickle cell, tay sachs). Pgs is genetic screening of each embryo. Before pgs, we transferred the best looking embryos and hoped that at least 1 took . Now with pgs, we know that many of these normal appearing embryos are genetically abnormal. Pgs allows the selection of genetically normal embryos and have improved the implantation and delivery rates.

Answered 11/28/2017

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