OTC Allergy: Not fair. Truly, it is trial-and-error. What works best for you might not work best for someone else. Loratadine is the weakest binding non-sedating antihistamine; Cetirizine is the strongest binding non-sedating antihistamine. Benadryl (diphenhydramine) works better than both but it makes people sleepy.
Answered 6/27/2014
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