Im 22 days late on my period i've taken 2 home pregnancy test both said negative .. my breast really hurt and some cramps now and then?

See a doctor: There are so many factors including and excluding pregnancy that can effect a cycle. A history, physical exam, and laboratory testing can help clear things up.

Blood test for HCG: If you had sex since your last period, you may wish to see your doctor for a blood test for HCG level to settle the issue. Have a healthy diet, exercise 30 minutes/day, drink plenty of water, have safe sex, no tobacco alcohol weed or street drugs. For nutrition: http://www.choosemyplate.gov/. Get HPV vaccine