What are the best antacid medications?

Depends on…: Frequency & severity of symptoms: mild, occasional heartburn can be relieved by otc antacids (tums/rolaids/mylanta/gaviscon). More frequent/severe may require otc h2 acid blocker (zantac/axid/tagamet/pepcid). Severe/frequent symptoms: try otc/rx ppi (prilosec/prevacid/protonix). Dietary changes help, too: no caffeine/soda, fried/fatty foods, spicy foods, onions, acidic foods (tomatoes, lemon, lime.