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A 42-year-old member asked:

Will chronic lymphocytic leukemia (cll) at stage 0 progress to stage 1, 2, 3 or 4?

2 doctor answers3 doctors weighed in
Dr. Michael Benjamin
Hematology and Oncology 24 years experience
Sometimes: Rai stage 0 cll infrequently progresses to higher-stage disease. The median survival is at least 130 months as reported in 2009: http://asheducationbook.Hematologylibrary.Org/content/2009/1/421/t2.Expansion.Html the disease is "heterogeneous, " which means that different patients have different experiences, making progression hard to predict in any one individual.
Dr. Binu Nair
Internal Medicine - Hematology & Oncology 20 years experience
It can : But typically depends on few specific abormalities we find by molecular analysis such as fish analyss, it in general stage 0 , may just do fine, but can progress to advanced stage late future, usually many years.

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