How is dapsone induced hemolytic anemia treated?

Stopping dapsone: The best way to treat Dapsone related anemia is by discontinuing dapsone. Dapsone causes hemolytic anemia which is dose-dependent and can be stopped only with discontinuing the drug. Usual practice is to use the lowest possible doses of Dapsone and support with vitamin E and folic acid.

Generally by ...: Stopping the drug first and foremost. Dapsone has two primary effects on the blood, both connected to its oxidant qualities. The first is dose-dependent hemolysis, which is more prominent in g6pd deficiency, and the second is methemoglobinenia, where heme fe is oxidized to the +3 oxidation state. Transfusion support may be necessary as a supportive measure.