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A 44-year-old member asked:

How is cholestasis of pregnancy diagnosed?

2 doctor answers3 doctors weighed in
Dr. Hector Chapa
Obstetrics and Gynecology 26 years experience
History/Physical/Lab: Cholestasis is diagnosed by doing a complete medical history, physical examination, and blood tests that evaluate liver function, bile acids, and bilirubin. Additionally, an ultrasound can de done to rule out gall bladder stones causing blockage. 1-2 preg/1000 is affected by cholestasis of pregnancy. It may be related to adverse pregnancy events like preterm labor, or at worse, stillbirth.
Dr. Miguel Cano
Obstetrics and Gynecology 31 years experience
Bile Acid levels: Cholestasis of pregnancy presents with total body itching, usually no rash, & diagnosis is usually made with an elevated level of bile acids. We also follow liver functions, treat with ursodiol (actigall) & monitor the fetus with twice weekly nsts & afi checks. Early delivery is usually warranted to avoid demise, no one really has a good explanation why this occurs. Take care.

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A 39-year-old member asked:

What is cholestasis of pregnancy?

2 doctor answers4 doctors weighed in
Dr. Hector Chapa
Obstetrics and Gynecology 26 years experience
See below please: Cholestasis of pregnancy is a condition in which the normal flow of bile in the gallbladder is affected by the high amounts of pregnancy hormones. Cholestasis is more common in the last trimester of pregnancy. 1-2 pregnancies/1000 are affected by cholestasis. In severe cases, but not all, cholestasis may increase the risks for fetal distress, preterm birth, or stillbirth. Blood tests are key.

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Last updated Dec 9, 2013
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