A 28-year-old member asked:
can a person with alpha thalassemia marry someone with beta thalassemia safely?
2 doctor answers
Dr. Robert Kwok answered
32 years experience Pediatrics
Yes: Marriage is no problem. Getting pregnant, however, may not be recommended if they have moderate or severe thalassemia. If they have only "trait", they will be fine if their children only inherit "no trait" or "trait from either mom or dad". If a child inherits "trait" from both mom and dad, the child might have a problem. A geneticist and hematologist can give more details for individual cases.
Answered on May 15, 2017
1
1 thank
Dr. Hasan Noubani answered
35 years experience Pediatric Cardiology
No : They will get at least 25% of babies with homozygous Alpha and 25% beta. So it is not safe.
Answered on Mar 28, 2017
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A 47-year-old member asked:
Dr. Michael Engel answered
19 years experience Pediatric Hematology and Oncology
Of course you can: A person can marry anyone they like. From a thalassemia perspective, and assuming your Alpha thal trait is in cis, your child has a 50/50 chance of b ... Read More
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A 41-year-old member asked:
Dr. Robert Kwok answered
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Traits, yes: Because the Alpha and beta thalassemia gene mutations are common, it is possible for a baby to inherit one from mom and another from dad. The child co ... Read More
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Dr. Jalal Zuberi answered
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Similar but differen: Alpha and beta thalassemia are distinct and different disorders since they diminish the production of distinct and different globin polypeptide chains ... Read More
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A 35-year-old member asked:
Dr. Robert Kwok answered
32 years experience Pediatrics
Traits, yes: Because the Alpha and beta thalassemia gene mutations are common, it is possible for a baby to inherit one from mom and another from dad. The child co ... Read More
1
1 thank
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