A member asked:

What class is pristiq (desvenlafaxine) in ssri's? and isnt pristiq (desvenlafaxine) a fairly new depression med.nd can it cause weight gain?

8 doctors weighed in across 5 answers
Dr. Alan Ali answered

Specializes in Psychiatry

Pristiq (desvenlafaxine): One of snris with lower potential for wt. Gain.

Answered 7/12/2012

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Dr. Alan Ali answered

Specializes in Psychiatry

Pristiq (desvenlafaxine): One of snris with less potential for wt. Gain.

Answered 8/12/2012

5.7k views

Thank
Dr. Pamela Pappas answered

Specializes in Psychiatry

Pristiq (desvenlafaxine): Pristiq is desvenlafaxine, actually a metabolite of venlafaxine (effexor). It's in the snri class -- inhibits reuptake of serotonin and norepinephrine in the brain. Being farther down the metabolic pathway, Pristiq may have less chance for drug interactions than some. Also this class in general may have less weight gain. Snri's do have more risk of agitation & suicidal ideation though.

Answered 6/30/2014

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Not SSRI: Pristiq (desvenlafaxine) is a snri (serotonin norepinephrine reuptake inhibitor). It is an antidepressant. Yes it can cause weight gain.

Answered 6/30/2014

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See NIH fact sheet: Nih fact sheet: http://www.Ncbi.Nlm.Nih.Gov/pubmedhealth/pmh0000449/ weight gain is not a listed side effect. It is a newer form of effexor, which is a very effective antidepressant. Desvenlafaxine is in a class of medications called selective serotonin and norepinephrine reuptake inhibitors (snris).

Answered 1/24/2014

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