A 38-year-old member asked:
why does excedrin always seem to cure my moody depression?
2 doctor answers
Dr. Lawrence Smith answered
29 years experience Clinical Psychology
"Secret ingredient": It could be the caffeine in the excedrine. It is possible that it is addressing some degree of caffeine withdrawal or just alleviating mild symptoms of fatigue, depressed mood, or irritability. Excedrine contains nearly the same caffeine as a shot of espresso.
Answered on Apr 12, 2016
Dr. Paul Pyles answered
32 years experience Addiction Medicine
Great Question: Excedrin contains caffeine, aspirin, and acetaminophen. It is possible that you are benefiting from the stimulating effect of the caffeine along with the anti-inflammatory and analgesic effects of the acetaminophen and aspirin helping you to feel better.
Answered on Jun 1, 2015
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