Depends: Orencia (abatacept) has not been implicated in development of heart failure (hf), but has also not been studied in patients wit hf (<1% of patients in clinical trials had hf). While its use is not contraindicated, it would be prudent to monitor your ejection fraction with echocardiogram every 6 months, perhaps bnp blood test in between and starting a beta blocker such as Carvedilol to protect against hf.
Answered 6/30/2014
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