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A member asked:
What cuases hypoplastic left heart syndrome?
A doctor has provided 1 answer
Multifactorial.: 2-6% recurrence risk with 1-2 prior affected siblings and up to 25% risk with rare familial autosomal recessive forms - both point to genetic underpinnings. The pathological changes center around severe aortic and mitral valve stenoses and hypoplasia/interruption of the aortic arch.
Answered 1/18/2018
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