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A 41-year-old member asked:

What's the difference between locoid (hydrocortisone butyrate) lipocream and clobetasol cream?

1 doctor answer1 doctor weighed in
Dr. John Ebner
Dermatology 18 years experience
Potency: Locoid (hydrocortisone butyrate) lipocream is a medium/low potency topical steroid while clobetasol is a ultra-high potency topical steroid. Clobetasol is more likely to cause side effects like skin thinning, scarring, discoloration which can all be permanent. Locoid (hydrocortisone butyrate) is much less likley to cause this. However, clobetasol is far more powerful than locoid (hydrocortisone butyrate). They are used for different conditions in different locations.

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Last updated Sep 28, 2016

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