A 48-year-old member asked:
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what is inheritance and pentrance of eds?

1 doctor answer
Dr. Gerry Tolbert
12 years experience Family Medicine
Depends: Ehlers danlos is a family of disorders, which has 6 major and several minor types. Given the multiple genes involved, it can be inherited in both autosomal dominant and autosomal recessive patterns, and can even spring from a de novo mutation. Penetrance depends on the type of mutation, and can therefore not be reliably calculated without more information.
Answered on Jul 1, 2014
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A 21-year-old member asked:
Dr. Ed Friedlander
43 years experience Pathology
Genetic: Ehlers-danlos syndrome is genetic, and is tremendously diverse -- from mere double-jointedness to life-threatening fragile vessels.
1
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A 21-year-old member asked:
Dr. Kathryn Riordan
37 years experience Rheumatology
EDS types: There are 6 major types of eds, they are inherited disorders marked by loose joints, hyper elastic skin that bruises easily, easily enlarged blood ves ... Read More
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A 45-year-old member asked:
Dr. Ronald Krauser
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Loose-jointedness: There are several variations of eds but they all have loose-jointedness as a primary symptoms. Increased elasticity of the skin may also be present.
A 44-year-old member asked:
Dr. Ricardo Alvillar
42 years experience Rheumatology
Genetic: The only common form of eds is type iii. This is because afflicted individuals rarely reach childhood; and, certainly not adulthood. Eds iii is an a ... Read More
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7 thanks

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