A member asked:

How does a procainamide challenge?

A doctor has provided 1 answer

Reveals Arrhythmia : Procainamide is a local anesthetic that acts on sodium channels. In the heart muscle sodium channels play a central role in the excitability of myocardial cells. So if you are given a bolus of this drug, it has the ability to increase the detection rate of an arrhythmia without losing predictive value. Meaning if it can produce an arrhythmia you may have a condition that needs to be treated.

Answered 6/30/2014

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