What are some cosmetic approaches to benign anisocoria?

None: Benign anisocoria is usually very subtle and tough for observers to spot. Anisocoria, or different sized pupils, can be from a number of neurological and ocular problems. But benign anisocoria is a minimal (about 1mm) difference between the pupils in an otherwise normal individual. If you have a larger difference than this i would see an ophthalmologist.

Treatment options: Since benign anisocoria is typically only 1-2 mm, most patients do not need treatment. If cosmetically undesirable, otc vasoconstrictor drops 1-2 times a day can be used on the eye with the smaller pupil to balance the pupillary sizes. If this is not acceptable, some patients will see their eye doctor who can prescribe alphagan (brimonidine) 3 times daily to the eye with the larger pupil.