Loss of Aldosterone: Metabolic acidosis (increased h+ and blood acidity) due to decreased bicarbonate (sodium bicarbonate) level in addisonian crisis is due to loss of the hormone aldosterone because sodium reabsorption in the distal tubule is linked with acid/hydrogen ion (h+) secretion. Less aldosterone stimulation of the renal distal tubule leads to sodium wasting in urine and h+ retention in the serum, resulting in bicarbonate (sodium bicarbonate) drop.
Answered 5/3/2018
6.2k views
Hydrogen ion control: Aldosterone levels are low in addison's disesse, aldosterone controls blood electrolyts, sodium, potassium and hydrogen, the latter is lost more in addison's, hydrogen is needed for the formation of bicarbonate (sodium bicarbonate).
Answered 6/18/2016
4.7k views
A doctor has provided 1 answer
A doctor has provided 1 answer
4 doctors weighed in across 2 answers
3 doctors weighed in across 2 answers
A doctor has provided 1 answer
90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.
Ask your question