Are the neurological effects of acute toluene exposure reversible?

Likely, mostly, yes.: Acute exposure is likely reversible if not long term. The neurotoxic effects of long term use (in particular repeated withdrawals) of toluene may cause postural tremors. Treatment with benzodiazepines provides some relief. The tremors associated with toluene misuse seem irreversible and continue after cessation of abuse. Hippuric acid is used to indicate exposure.