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A 33-year-old member asked:

saliva cortisol test - how accurate can a saliva test be?

2 doctor answers2 doctors weighed in
Dr. Richard Shewbridge
Endocrinology 33 years experience
Very accurate.: Saliva cortisol test is great for finding out if you are overproducing cortisol. Collected at midnight (assuming a normal sleep/awake pattern), salivary cortisol level is normally very low. When elevated, it indicates that a patient may be overproducing cortisol (cushing syndrome). The salivary cortisol test is not a good test for detecting underproduction of cortisol (adrenal insufficiency).
Dr. Gary Alder
Dentistry 47 years experience
Check normal range: Accuracy of all tests is an issue and if the test does not reflect what appears clincally it may be need to be repeated. Accuracy depends on sensitivity and specificity. Trials need to be run comparing blood and saliva to determine which is best... And which is best for the money.

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Similar questions

A 36-year-old member asked:

Why is my saliva cortisol result so high? Is saliva testing not as accurate?

1 doctor answer1 doctor weighed in
Dr. Susan Wingo
Endocrinology 33 years experience
High cortisol: High cortisol may be due to a number of conditions, including a tumor in the pituitary gland or adrenal gland(s), stress, pain, illness, or taking steroids, or something that interferes with the test. The only way to find out what is causing your cortisol level to be high is to work together with a doctor.
CA
A 28-year-old male asked:

What is the definition or description of: saliva cortisol?

4 doctor answers10 doctors weighed in
Dr. Robert Brodsky
Dentistry 58 years experience
Salivary cortisone: Cortisone in the saliva can mean a disease that produces too mych cortisone. Cuchings disease is one of these.
A 48-year-old member asked:

I received slightly high saliva cortisol levels from recent test. What is a good approach to deal with this?

2 doctor answers3 doctors weighed in
Dr. Brad Eilerman
Endocrinology 20 years experience
Salivary Cortisol: First, ensure the test was at or near midnight. There are not well recognized standard values for disease processes outside the midnight timing. 2nd, get a 24 hour urine cortisol. A normal 24 hour cortisol may indicate either a cyclic process or a physiologic change with cortisol (a reaction to a stressor, disrupted diurnal rhythm, obstructive sleep apnea). If high - Dexamethasone suppression.
CA
A 33-year-old female asked:

Seeing endo soon, but i would like to understand my saliva cortisol test result. 1.94 mcg/dl (rr is < or = 0.09 mcg/dl) cushings r/o in 2012.

2 doctor answers3 doctors weighed in
Dr. Dan Fisher
Internal Medicine 27 years experience
Wait to see endo.: Best left to endo. It is hard to interpret these numbers as timing, age and assay specific factors are at play. Can't figure those all out here. You will need someone who can understand how this test fits into the big picture.

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Last updated Oct 3, 2016
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