What could cause low libido and no pleasure out of sex?

Lots of issues: Low libido/sex drive plus lack of pleasure from sex is a complicated issue. Take a look at your life. Any stress re work, money, family, friends, etc. Take a look at your health. Good or bad? Any chronic conditions? Medications? Depression? Do you smoke? Any other (illicit) substances? Or alcohol to excess? Consider addressing all this w/your family doc who can order a set of labs to evaluate.

Many causes: This needs to be addressed individually, in that it could be anything from exhaustion to pain instead of pleasure with sex to relationship problems.. Or other reasons.

Agree with Dr. L: It is not feasible to provide a meaningful opinion without taking additional history, physical examination and may be some tests. It would be prudent to see your doctor and discuss if you may be depressed. Counter-intuitive as it may seem, exercise may help. Start with low intensity exercise such as walking and gradually increase the intensity as tolerated.