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A 44-year-old member asked:

What's involved in allogeneic stem cell transplantation?

2 doctor answers6 doctors weighed in
Dr. Joseph Woods
Pathology 28 years experience
Donor matching.: This involves two people: the (healthy) donor and the (patient) recipient. Donors must have a tissue (hla) type that matches the recipient. Matching is performed on three or more loci of the hla gene, and a perfect match at these loci is preferred. Even with this, immunosuppression is often needed due to graft vs host disease.
Dr. Keith Stockerl-Goldstein
Hematology and Oncology 30 years experience
Chemo +/- radiation: The first part of an allogeneic stem cell transplant involves giving chemotherapy and/or radiation to the patient. Then the stem cells from a donor are infused intravenously. There are many risks and side effects possible with this treatment but it can help cure many diseases.

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Last updated Aug 19, 2013
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