A 31-year-old member asked:
what is the relationship between hypertension and cardiac output?
2 doctor answers
Dr. Michael Fenster answered
30 years experience Cardiology
Mathematical: The relationship can be expressed as a variant of darcy' law; flow (q) = pressure/resistance. In the human circulatory system: q = (map – rap)/tpr (map = mean aortic (or arterial) blood pressure in mmhg, RAP = mean right atrial pressure in mmhg and tpr = total peripheral resistance in dynes-sec-cm-5.) however, as map>>rap, , this can be simplified to: q~map/tpr. Map is obviously affected by htn.
Answered on Mar 13, 2019
Dr. Bennett Werner answered
43 years experience Cardiology
Complicated: The equation is: co equals bp/total peripheral resistance. If tpr is constant, co rises when BP rises but since that isn't the case, there is a complicated relationship between co and BP which tends to be unpredictable. Tpr is the resistance of the blood vessels and depends on blood viscosity, radius of the vessels to the 4th power, and length and # of vessels & depends on arteriolar tone.
Answered on Jun 10, 2014
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