A member asked:

Should a patient who is on methatraxate be given the shingles vacine?

6 doctors weighed in across 2 answers
Dr. Ralph Morgan Lewis answered

Specializes in Family Medicine

Shingles vaccine?: Methotrexate suppresses the immune system, one condition that is a contraindication to giving the shingles vaccine (since it is a weakened live virus vaccine); so no, pts on mtx should not be given shingles vaccine.

Answered 6/28/2014

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Dr. Thomas Namey answered

Specializes in Rheumatology

No issue!: The methotrexate is activated by a process called polyglutimization. It takes 2 and one half months! Missing two MTX shots is meaningless!

Answered 10/23/2017

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