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A member asked:
Does antihistamine make you drowsy?
A doctor has provided 1 answer
Older ones do: First generation antihistamines (benadryl, clor-pheramine, atarax) cross the blood brain barrier and cause lethargy. Second generation (allegra, claritin, zyrtec, xyzal, (levocetirizine) clarinex) cause the blood brain barrier at a much lesser amount and more targeted to the h1 receptor.
Answered 9/16/2019
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