Taking cyclosporine due to liver transplant. i have sinus infection with cold, can i take nimesulide?

No: Nimesulide is a non-steroidal anti-inflammatory drug not available in many countries due its hepatotoxic effects. You should especially not take it. Try a cool mist humidifier, filled with one bottle of hydrogen peroxide and two bottles of water. That gives you an aerosolized mist of 1% H2O2--which will kill virus and bacteria on contact, and breaks down into water and oxygen.