A member asked:

Why does primary hyperaldosteronism cause metabolic alkalosis?

2 doctors weighed in across 2 answers

Simplfied Version: Aldosterone causes reabsorption of Na and secretion of K+ and H+, so if you have too much aldosterone, you'll secrete too much H+, lose too much acid, and have an alkalosis state ;) Simplified explanation Cheers C

Answered 1/2/2015

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Dr. Clarence Grim answered

Specializes in Endocrinology

Conn 's alkalosis : Aldo moves Na from urine and K and H out into urine. Lowering H in blood makes you more alkalotic. Also as K moves out of cells to keep blood K up H moves into cells. Less H in blood = higher pH.

Answered 9/24/2015

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