If Mom is 36 at term: risk of having a fetus with DS at 16 weeks' gestation is 1:200; risk of having a full-term baby with DS is 1:275. If mom is 37 at term, risk at 16 weeks is 1:150; at term, 1:225, because some pregnancies are lost. Comprehensive 1st trimester screening & integrated 1st & 2nd trimester screening calculate risk by specific hormone & protein levels in mom's blood + fetal ultrasound + maternal age.
Answered 1/11/2015
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