What can you tell me about barth syndrome?

Barth Syndrome, or : 3-methylglutaconic aciduria type II, is caused by mutation of the gene on Chr. Xq28 that codes for tafazzin, an enzyme needed for synthesis of cardiolipin, a component of the inner mitochondrial membrane needed for energy production. Each son of a carrier mom has a 50% chance of having Barth syndrome; each daughter, a 50% chance of being a carrier. See barthsyndrome. org/about-barth-syndrome.