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A member asked:
What is the actual cause of b12 (cyanocobalamin) deficiency in the body in pernicious anemia?
A doctor has provided 1 answer
No intrinsic factor: B12 in the diet usually binds to intrinsic factor in the stomach and then gets absorbed by the small bowel. In pernicious anemia, there is low or no intrinsic factor being made by the stomach cells. As a result, there is gradual deficit of B12 stores and eventaully as all the B12 is gone the new red blood cell production is affected.
Answered 9/28/2016
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Related Questions
A member asked:
How low does level of vitamin B12 need to be considered deficiency anemia?
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Please what's the difference between pernicious anemia and vitamin B12 deficiency.my iron levels are perfect.I'm getting injections for vitamin b12.
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Hi I have vitamin B12 Deficiency. Doc didn't say pernicious anemia. Everyone said I'm going to get cancers.god im so scared. I've started injections?
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I was wondering is B12 deficiency the same as pernicious anemia?
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2 years ago, i was told my B12 deficiency could lead to pernicious anemia. I stopped the B12 pills, my symptoms match, can I have this? B12 now fine.
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