Can ibuprofen be taken with prednisone? the last dose was taken approximately 21 hours ago.

Yes but...: These can be taken together and they are very commonly prescribed as such but you have to be careful due to the increased risk of gastrointestinal bleeding especially if you have a history of stomach ulcers. Both can also cause swelling. Make sure you take them with food and if you develop abdominal upset hold them and talk to your doctor.