Is there one ingredient that helps the skin more than others?

No.: The skin is the largest organ in the body, it has multiple defenses and functions that keep your body separate and protected from the rest of the world. Skin, including mucous membranes (mouth, anus) has the most complex nerve supply. So, depends on person, skin disorder, symptoms. Generalities:: if dry, moisten it; if moist, dry it; if infected, antibiotic it; most everything else, cortisone -:).