A member asked:

What is the mitochondrial disease known as l.h.o.n.? how is it treated?

5 doctors weighed in across 2 answers
Dr. Susumu Inoue answered

Specializes in Pediatric Hematology and Oncology

Hereditary blindness: LHON stands for Leber's hereditary optic neuropathy. It is inherited from mother to child. Usually a young man loses eyesight in the enter of one eye,and shortly after he loses eyesight in other eye. Women are less often affected. Gene mutations that are responsible for this disease is known. There are no curative treatments. If you carry this gene, you should avoid smoking, alcohol certain drugs.

Answered 12/31/2016

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Progressive vision: loss occurs as a result of this condition which is the most common known mitochondrial disease. About 45 mutations have been linked to LHON. Although it is the most common, it is nevertheless rare and must be treated at a center with knowledge of and experience with mitochondrial disorders.

Answered 10/23/2017

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