A 39-year-old member asked:
What type of mutation causes thalassemia?
1 doctor answer • 2 doctors weighed in
Pediatrics 36 years experience
Hemoglobin: formation is affected in thalassemia. Mutation in one or both of the genes responsible for the production of hemoglobin proteins (alpha and beta globin) lead to decreased production of these proteins, decreased hemoglobin formation and resulting anemia.
3.4k viewsReviewed >2 years ago
A 46-year-old member asked:
What type of mutation causes thalassemia minor?
1 doctor answer • 3 doctors weighed in
Pediatric Hematology and Oncology 20 years experience
Many: Many mutations in beta-thal genes will cause a decreased production, rather than an absence of production. Inheritance of one f these genes will cause a thalassemia minor. In alpha-thalassemia, the inheritance of two mutations (out of four genes) can provide mild or no symptoms that are typical of thalassemia minor.
5.7k viewsReviewed >2 years ago
Last updated Apr 23, 2018
Connect with a U.S. board-certified doctor by text or video anytime, anywhere.
24/7 visits - just $39!
50% off with $15/month membership
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.