A member asked:

What is cytotoxic hypersensitivity (type 2)?

A doctor has provided 1 answer
Dr. Al Hegab answered

Specializes in Allergy and Immunology

Type II hypersensitivity: Or cytotoxic reactions, are antibody dependent, IgG or IgM binds to the own body cell surface after being altered by a protein, so the immune system recognizes as non-self (foreign) attacks and destroys the cell by fixing a protein called complement, which in turn forms the Membrane Attack Complex and destroy the cell, the most famous is hemolytic anemias and some auto immune diseases

Answered 3/23/2020

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