A member asked:

What does maternal age have to do with the possibility of down syndrome?

A doctor has provided 1 answer

Statistical risks: The risks of DS are at the low point in the early twenties, (~1/2700) and climb past 1/100 at 45 and over 1/20 after 55. The usual explanation is the accumulated toxic events of a woman's life can cause the eggs that sit in her ovary to become damaged as they age.

Answered 11/29/2014

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