A member asked:

Can you take zofran (ondansetron) for a hangover?

6 doctors weighed in across 4 answers

Severe nausea: and vomiting are the ONLY indications. These best mediciation for hangover is rehydration with 8-10 glasses of electolyte rich fluids ( Powerade, Gatorade, Vitamin water). Zofran (ondansetron) is NOT indiciated for a hangover

Answered 2/24/2020

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Dr. Stuart Hickerson answered

Specializes in Family Medicine

Yes: if you are nauseated Zofran (ondansetron) should help and be safe.

Answered 9/26/2019

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Helps with...: Zofran (ondansetron) is a medication used for nausea and vomiting. If these are the symptoms you are experiecing then it should help with that. However, it will not necessarily help with any other hang over symptoms you might have( headache, dizziness, malaise, etc.) if you have those.

Answered 6/9/2018

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Dr. Jason Burke answered

Specializes in Anesthesiology

Yes: I operate the only medical practice dedicated to hangovers and we give zofran (ondansetron) all the time. If you have a headache as well, you will need to deal with the headache, as headaches contribute to the nausea, especially in women.

Answered 11/2/2019

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